A Brief History of Ketamine

A Brief History of Ketamine

The unique story of ketamine began in 1956 with the synthesis of the drug, phencyclidine. Found to be a remarkable anesthetic for monkeys, phencyclidine was then used on humans after numerous animal testings. Unfortunately, the side effects that researchers observed in some patients were concerning. Instead of waking peacefully from anesthesia, some patients experienced acute emergence delirium lasting hours after their operation was over. They described feeling sensory deprived and the loss of sensations in their limbs. Further studies concluded that phencyclidine produced a sensory deprivation syndrome.

Ketamine for Trigeminal Neuralgia

Ketamine for Trigeminal Neuralgia

Trigeminal neuralgia (also known as tic douloureux) is a chronic pain condition affecting the fifth cranial nerve (1).  There are twelve cranial nerves that emerge from the brain and cranial nerve V carries sensation from the face to the brain.  Trigeminal neuralgia occurs at a rate of 4.3 per 100,000 people per year (2). There are two main types: classic trigeminal neuralgia and atypical trigeminal neuralgia (3).  It is vital to consult with a specialist and confirm the diagnosis, which may include neurological testing and MRI of the brain (4).  Both of these diagnoses can be extremely painful, debilitating, and especially frustrating when multiple traditional treatment options are not effective in relieving pain.

The Bio-Psycho-Social-Spiritual Model of Medicine

The Bio-Psycho-Social-Spiritual Model of Medicine

At Reset Ketamine, we take a bio-psycho-social-spiritual approach to medicine.   Dr. Ko's medical training is from the University of Rochester School of Medicine & Dentistry. This is where the biopsychosocial model was founded.  For example, when someone comes in with chest pain, we’re not only looking at the organic or biological causes of chest pain, i.e heart attacks, pneumothorax, aortic dissection, fractures, pneumonia, costochondritis, etc. 

14 Insights from the American Society of Ketamine Physicians’ Inaugural Conference 2018

14 Insights from the American Society of Ketamine Physicians’ Inaugural Conference 2018

The key to providing outstanding service to our patients is to keep educated and up-to-date. This month, we got to do so at the inaugural conference of the American Society of Ketamine Physicians (ASKP) in Austin, Texas.

We learned a massive amount from leaders in the field of ketamine research and treatment at the conference. While we want to share it all, we kept it simple and are sharing 14 insights from this conference with you!

Set and Setting During Ketamine Infusions

Set and Setting During Ketamine Infusions

There are two important factors to consider when undergoing your ketamine infusions. These are the patient’s mindset (set) and the environment (setting) where the infusion will occur.  Mindset is shortened to “set” and refers to the mental state a person brings to the clinic, including the motives, intention, beliefs, along with the physical, emotional, & cognitive state before the infusion (1).  Setting refers to the physical and social environment where the ketamine experience will occur.  This includes the physical environment (both inside & outside), the healthcare team in the room, as well as the person who brought you to the clinic.   At Reset Ketamine, we highlight these two factors because we know it will affect the ketamine experience tremendously.

Ketamine's Use to Treat Substance Use Disorders

Ketamine's Use to Treat Substance Use Disorders

In our last post, we answered the question, “Is Ketamine Addictive?”  Now, we want to share ketamine’s anti-addictive properties. In the past year, 20.2 million American adults (8.4%) had a substance use disorder.  Addiction is frequently seen in conjunction with mood disorders and may actually be a form of self-medication in these patients.  So can ketamine play a role in treating these patients, especially those with dual diagnoses?

5 Ways to Maximize Progress After Your Ketamine Infusions

5 Ways to Maximize Progress After Your Ketamine Infusions

Ketamine is revolutionizing treatment of pain, depression, and anxiety. However, it is most effective when viewed as a catalyst.  It would simply be untrue to tell you that all you need is ketamine.  Treatment of mood and pain disorders are complex, and ketamine is one part of the solution.  Ketamine can absolutely help you get going in a way no other traditional treatment has done before. So once you receive your ketamine infusions, use this momentum for change!  Here are to 5 ways to maximize your progress: 

23 Books to Enhance Your Healing and Growth

23 Books to Enhance Your Healing and Growth

In honor of National Book Lover’s Day, we are sharing our favorite nonfiction and fiction books! These books range from advice from top performers in the world, to guidance on how to transform your life, all the way to stories which warm and inspire the soul.

Have you read any of these? If not and you are curious to read them, do what we do at Reset Ketamine and head over to the library, or click on the book image and you’ll get over to Amazon so you can buy and add it to your personal library.

3 Must Read Scientific Articles About Depression and Ketamine

3 Must Read Scientific Articles About Depression and Ketamine

Want to know more about how ketamine works? Especially curious about how it transforms the lives of those with depression, anxiety, and pain?  Love science?  A google or PubMed search will give you numerous articles on this topic.  At Reset Ketamine, we are big readers and lovers of learning so we found three articles you should check out regarding depression and ketamine...especially if you are science nerds like us! 

What to Expect During your Ketamine Infusion

What to Expect During your Ketamine Infusion

Perhaps you’ve decided to try ketamine infusions for your depression, anxiety, PTSD, or chronic pain.  Or maybe you have yet to decide and want a little more information. Some level of nervousness is normal and very common when facing something new, especially something that is so cutting-edge. To ease some of your worries, we’ll share with you four things to expect during your ketamine infusions…

3 Reasons Why You Should Know About the Default Mode Network of Your Brain

3 Reasons Why You Should Know About the Default Mode Network of Your Brain

The Default Mode Network (sometimes called simply the default network or the DMN) refers to an interconnected group of brain structures that are hypothesized to be part of a functional system. The DMN includes areas of the brain which researchers found to have higher activity when the mind was supposed to be at rest.  For example, when you are day dreaming, thinking about the future, replaying memories, etc. without a specific goal in mind.  Now, why would we care about this? The DMN is found to have increased activity in certain mood and pain disorders.  That being said, let's look at our 3 reasons why you should know about the DMN. 

Ketamine Infusion Protocol: Twice a Week or Three Times a Week?

Ketamine Infusion Protocol: Twice a Week or Three Times a Week?

Ketamine infusions are at the frontier of treating depression, anxiety, PTSD, OCD, and pain disorders. And just like the pioneers of the Wild West, ketamine physicians are also trailblazers. Ketamine infusionists create their protocols based on studies and the responses of their patients to treatment. Since ketamine is still a relatively new treatment, researchers are still investigating the optimal dose and frequency.