There are two important factors to consider when undergoing your ketamine infusions. These are the patient’s mindset (set) and the environment (setting) where the infusion will occur. Mindset is shortened to “set” and refers to the mental state a person brings to the clinic, including the motives, intention, beliefs, along with the physical, emotional, & cognitive state before the infusion (1). Setting refers to the physical and social environment where the ketamine experience will occur. This includes the physical environment (both inside & outside), the healthcare team in the room, as well as the person who brought you to the clinic. At Reset Ketamine, we highlight these two factors because we know it will affect the ketamine experience tremendously.